- Sage Court
- Sagittario Street
- Saint Andrews Court
- Saint Andrews Drive
- Saint George Street
- Saint James Street
- Saint Patrick's Drive
- Saint Paul Avenue
- Salisbury Avenue
- Salt Springs Church Road
- Sanderson Street
- Sandhurst Court
- Sandlewood Avenue
- Sandra Street
- Sandy Row
- Sarah Street
- Savannah Oaks Drive
- Scarfe Avenue
- Scarfe Gardens
- Schertzberg Lane
- Scotia Avenue
- Second Avenue
- Secretariat Court
- Seneca Crescent
- Seventh Avenue
- Shaftesbury Avenue
- Shalfleet Boulevard
- Shannon Street
- Shantz Avenue
- Sharp Road
- Shaver Road
- Shaver Street
- Sheena Avenue
- Sheffield Avenue
- Sheldon Street
- Shellard Lane
- Shellington Place
- Shenstone Place
- Sheppard Street
- Sheridan Street
- Sherman Drive
- Sherry Lane
- Sherwood Drive
- Shorwell Place
- Sigurd Jensen Court
- Simpson Street
- Sinclair Boulevard
- Sinden Road
- Sixth Avenue
- Sky Acres Drive
- Skylark Road
- Slater Street
- Smith Road
- Smith's Lane
- Somerset Road
- Sour Springs Road
- South Street
- Southglen Road
- Spalding Drive
- Spartan Drive
- Spring Lane
- Spring Street
- Springfield Drive
- Sprucehill Drive
- Stanley Street
- Steed Court
- Stephenson Road
- Sterling Street
- Stewart Street
- Stinson Avenue
- Stirton Avenue
- Stockdale Drive
- Stodola Drive
- Stowe Terrace
- Stratford Terrace
- Strathcona Avenue
- Strawberry Lane
- Strong Court
- Stymie Boulevard
- Suddaby Court
- Sudds Lane
- Sulky Road
- Summerhayes Crescent
- Sunset Avenue
- Superior Street
- Sussex Avenue
- Sycamore Drive
- Sydenham Street
- Sympatica Crescent