- Oak Park Road
- Oak Street
- Oakhill Drive
- Oakley Road
- October Place
- Old Farm Road
- Old Greenfield Road
- Old Onondaga Road
- Old Onondaga Road East
- Old Onondaga Road West
- Old River Road
- Old Saw Mill Road
- Olive Tree Road
- Oliver Court
- Omega Drive
- Oneida Drive
- Oneida Street
- Ontario Street
- Orchard Avenue
- Oriole Parkway
- Orkney Place
- Osborn Avenue
- Osijek Crescent
- Owen Avenue
- Oxbow Lane
- Oxbow Road
- Oxford Street