- Sailors Hope Road
- Saint Catherines Road
- Saint Charles Road
- Sandys Lane
- Sanko Lane
- Scotia Drive
- Sea View Lane
- Selkirk Road
- Sheehan Road
- Sheep Pond Road
- Shipbuilding Lane
- Shipwreck Lane
- Smokey's Lane
- Snake Road
- Souris Line Road - Route 305
- Souris River Road
- Souris River Road - Route 358
- South Road
- Spry Point Road
- Steeles Lane
- Sterns Avenue
- Sunset Drive