- Saint Edmunds Crescent
- Sandy Pines Trail
- Sauble Falls Parkway
- Sauble Falls Road
- Sauble Place
- Sauble Woods Crescent
- Second Avenue North
- Second Avenue South
- Second Street North
- Second Street South
- Seventeenth Street South
- Seventh Street North
- Silver Lake Crescent
- Silver Lake Road
- Simcoe Avenue
- Sixth Street North
- Sixth Street South
- Southampton Parkway